Effects of Wild Blueberry Consumption on Cognitive Function in Older Adults

Researcher(s)

  • Katherine Rippon, Dietetics, University of Delaware

Faculty Mentor(s)

  • Sheau Ching Chai, Health Behavior and Nutrition Sciences, University of Delaware

Abstract

Having a strong memory is critical for older adults in maintaining quality of life as they age. An estimated 6.7 million American adults aged 65 or older are currently living with Alzheimer’s disease. Additionally, some subjective cognitive decline (SCD), or worsening memory, can naturally occur with aging. Previous research suggests that long-term supplementation of antioxidant-rich fruits may reduce age-related cognitive decline. Specifically, blueberry consumption can improve aspects of cognition and may reduce the risk of neurodegenerative diseases. Recent studies have shown that daily supplementation of wild blueberries for 12 weeks was associated with improvements in immediate word recall, episodic memory, and executive function. Blueberries are rich sources of polyphenols (bioactive ingredients in plants) including anthocyanins and flavonoids, which are phenolic metabolites. Polyphenols are known for their strong antioxidant and anti-inflammatory properties. Consuming fruits rich in these compounds may strengthen memory and have positive impacts on cognitive function. 

This study examined the relationship between daily wild blueberry consumption and cognitive function in generally healthy older adults. In this ongoing randomized controlled trial, 15 participants (6 men and 9 women) between the ages of 60 and 80 years old were included. Qualified participants were randomized into two groups and asked to consume 24 grams of either freeze-dried wild blueberry powder or placebo powder daily for 12 weeks. Anthropometric and resting blood pressure measurements were taken during the visits. Cognitive function was assessed using the Wechsler Adult Intelligence Scale—Fourth Edition Digit Span subtest and the Cambridge Neuropsychological Test Automated Battery (CANTAB) scores. This study is ongoing and data collection is expected to conclude in the summer of 2024. Limitations with the current group of participants include small sample size and narrow population demographics.